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It is also worth noting that in obese patients with T2DM, GLP-1RA-mediated weight reduction has been associated with the detection rate of breast cancer [34], with the highest incidence observed in patients who experienced more than 10% weight loss following treatment [35]

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For example, beta-blockers, such as propranolol, which are commonly used to treat high blood pressure and other heart-related conditions, may reduce blood flow to the hands and feet